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Diverse Effects of 3 Selective Serotonin Reuptake Inhibitors on Bruxism in a Depressive Patient Treated With Botox Therapy A Case Report

Muhammed Isa Kara, DDS, PhD, Emrullah Ozen, DDS, www.psychopharmacology.com

August 2016

Sleep bruxism (SB) is defined as a stereotyped oromandibular activity during sleep, which is characterized by involuntary grinding and/or clenching of the teeth. It may cause a variety of problems in the orofacial region and affect the dental structure.

Temporomandibular Myofacial Pain Treated with Botulinum
Toxin Injection

Niv Mor, Christropher Tang and Andrew Blitzer

July 2015

This article reviews the diagnoses and treatment of temporomandibular disorders (TMD) and outlines of the role of botulinum toxin (BoNT) in the treatment of myofacial TMD. This manuscript includes a brief history of the use of BoNT in the treatment of pain, the mechanism of action of BoNT, and the techniques for injections, adverse effects and contraindications when using BoNT to treat mayofacial pain caused by TMD.

Botox in Dentistry: The Healing Side of a Poison

Mini Jain, Abhishek Bansal, Disha Agarwal, Monika Joshi

January 2014

We can’t deny the fact that we all thrive to look young so called less than our age. And botox is one option which claims to give a younger and more esthetic look to people of advancing age groups. Today BOTOX is the name which is hottest in the field of cosmetic and esthetic industry. There is no question that BOTOX and dermal fillers are well known for their esthetic results in terms of smooth skin and replacing lost volume in face , especially the oral and perioral areas.

Botulinum Toxins in Dentistry — The New Paradigm for
Masticatory Muscle Hypertonicity

Singapore Dental Journal

December 2005

The use of botulinum toxin in the dental office for the treatment of dentally related conditions including parafunctional clenching, extracapsular myogenic temporomandibular disorder (TMD), trismus, and the associated headaches is a new option for symptom relief in patients in whom conventional treatments are not effective. Used appropriately and with a fully informed patient who understands that no treatment is guaranteed, botulinum toxin injections represent a different treatment protocol for patients who visit their dentists seeking relief from these conditions.

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Restylane Contour Is a New Cheek Filler With Some Unique Distinctions

Melanie Rud

Jul 1, 2021

There’s certainly no shortage of various hyaluronic acid fillers to choose from these days, with plentiful options for each and every area of the face. But the latest one to hit the market, Restylane Contour, touts some unique and noteworthy differences.

It’s approved by the U.S. Food and Drug Administration (FDA) for cheek augmentation, a procedure having a major moment as of late—cheek filler searches increased by 218% between 2018 and 2020 (this, according to Galderma, the makers of the Restylane family of fillers). On RealSelf, dermal fillers were among the most discussed procedures by consumers and providers in 2020. “Cheeks are the cornerstone of the face, and focusing on natural contour and not just volume loss can result in a dynamic expression that amplifies their natural beauty,” says Dr. Leslie Baumann, a board-certified dermatologist in Miami and a lead investigator in the clinical trial of Restylane Contour. “Hyaluronic acid levels in the skin diminish as we age, causing the face to lose shape while increasing the likelihood that wrinkles and folds will appear.”

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Dysport DREAM Study

Galderma Laboratories

June 2020

A twice-yearly treatment schedule of Dysport® injections in the glabellar region was evaluated for subject satisfaction, efficacy, and safety to reflect real-world treatment frequencies.

High subject satisfaction was achieved with twice-yearly treatments of Dysport®with median time to onset of 2 days, long duration, and low reports of adverse events.

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Facial expressions affect photo comparability

Lisette Hilton


Researchers report in a new study that 16 facial expressions and head positions significantly impact malar and jowl volumes, with smiling and frowning having the biggest effects. Facial volume changes from expressions can look like results seen from aesthetic facial rejuvenation procedures.

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New Dysport injection technique

Lisette Hilton


Researchers using a new technique for injecting abobotulinumtoxinA (Dysport, Galderma) to treat glabellar lines found it might be more likely to result in patient satisfaction than the conventional approach, according to a study published in the February 2019 Journal of Cosmetic Dermatology.

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Aesthetics Complications Guidelines

Aesthetics Complications Author Group

June 2018

The ACE Group developed a series of evidence-based, peer-reviewed guidelines that cover complications that can occur in nonsurgical aesthetic practices. The objective of this series is to help dermatologists and other physicians performing aesthetic procedures identify and manage these potential complications. Each guideline was produced after a vast literature review by leading experts in the United Kingdom. We hope these guidelines help raise treatment standards within the medical community and ensure early diagnosis and appropriate management of complications, ultimately improving outcomes for our patients.

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The efficacy and complications of a new technique of Abobotulinum-toxin A (Dysport) injection in patients with glabellar lines

Esmat Karbassi MD, Nouzar Nakhaee MD, Maryam Zamanian PhD


Botulinum toxin has many applications in medicine. In dermatology, it is most frequently used for the treatment of frown lines approved by US food and drug administration.1,2 This neurotoxin protein acts at the neuromuscular junction by inhibiting the release of acetylcholine into the nerve endings, which causes weaken the contraction of the facial muscles and consequently result in the decrease in…

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Outcomes of Polydioxanone Knotless Thread Lifting for Facial Rejuvenation

Dong Hye Suh, MD, PhD, Hee Won Jang, MD, Sang Jun Lee, MD, PhD, Won Seok Lee, MD, and Hwa Jung Ryu, MD, PhD


The process of aging changes the shape, texture, and color of the face. Facial shape is mainly transformed by uneven descent and laxity of the skin and soft tissues. Texture is primarily determined by fine wrinkles and pores of the skin.

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The First Case Report of a Systemic Allergy to OnabotulinumtoxinA (Botox) in a Healthy Patient

Lorne King Rosenfield, MD, FACS; Dean George Kardassakis, MD, FACP; Kristen Anne Tsia; and Grace Stayner


OnabotulinumtoxinA, also known as Botox Cosmetic (Allergan, Inc, Irvine, California), is the most commonly injected substance to diminish the appearance of facial wrinkles; it functions cholinergically by relaxing the muscles surrounding the injection site. Botox Cosmetic is a purified version of a toxin produced by the bacterium Clostridium botulinum.

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Pushing Back the Clock

Natausha Spears, RN


Natuasha Spears, RN, IAFA Board Member and internationally certified injectable trainer recently had an article published in Thrive Oklahoma, Sept/Oct 2014, Volume 5-Issue 5, page 42 entitled “Pushing Back the Clock”.

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Blood Facial…Is it right for you?

Natausha Spears, RN


Due to the rise in lifestyle education and wider availability, the platelet rich plasma or PRP facial has become very popular lately.

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Hyaluronic Acid Gel Distribution Pattern in Periocular Area With High-Resolution Ultrasound Imaging

Alice S. Goh, MBBS, MS; Jocelyne C. Kohn, MD; Daniel B. Rootman, MD, MSc; Joseph L. Lin, MD; Robert A. Goldberg, MD


High-resolution ultrasound (HRUS) imaging has been used to study the anatomy and dynamic soft tissue relationships of the periocular area (Figure 1). With the ability to reveal expansible changes such as fat prolapse or fluid accumulation, HRUS has been proven to be a useful tool in defining and improving the outcomes of periocular rejuvenation.

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Triple-blind, prospective, internally controlled comparative study between abobotulinumtoxina and onabotulinumtoxina for the treatment of facial rhytids

Ramtin Kassir, Aparanjita Kolluru, Martin Kassir


OnabotulinumtoxinA (ONA) has been used since the early 1980s for reducing muscle spasms in medical illnesses. Over the past 20 years, ONA has been recognized by regulatory authorities in approximately 80 countries worldwide as an effective treatment for 21 different medical uses including strabismus, blepharospasm, cervical dystonia, and severe primary axillary hyperhidrosis. Its use as a cosmetic agent..

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A Blanching Technique for Intradermal Injection of the Hyaluronic Acid Belotero

Patrick Micheels, M.D., Didier Sarazin, M.D., Stéphanie Besse, M.D., Hema Sundaram, M.D., Timothy C. Flynn, M.D.


Anatomically, the dermis is divided into two clearly distinguished parts: the papillary dermis and the reticular dermis. The papillary dermis, located between the basal layer of the epidermis and the reticular dermis, has a different fibrillar structure from the reticular dermis. In the papillary dermis…

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Filler injections with the blunt-tip microcannula compared to the sharp hypodermic needle

Luc Dewandre MD, Caroline Caperton MD,MSPH, James Fulton MD,PhD


Injectable fillers have become popular cosmetic procedures with more than one million injections done annually. These augmentations are usually performed with hypodermic needles, often supplied with the product. Numerous problems maybe associated with needles…

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Induction of Dermal Collagenesis, Angiogenesis, and Adipogenesis in Human Skin by Injection of Platelet-Rich Fibrin Matrix

Anthony P. Sclafani, MD; Steven A. McCormick, MD


Since the time of pare, modern surgical care has relied on optimization of local tissue conditions to allow wounds to heal unimpeded. With an improved understanding of the effects of local growth factors, surgeons have begun to manipulate the wound environment to promote more rapid and effective healing.

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Platelet-rich plasma induces increased expression of G1 cell cycle regulators, type I collegen, and matrix metalloproteinase -1 in human skin fibroblasts

Jae-We Cho, Sung-Ae Kim, Kyu-Suk Lee


Platelet-rich plasma (PRP) is a blood-derived fraction containing at least 100 thousand platelets (1). In clinical applications PRP has been used to facilitate bone proliferation in nonunion fractures of joint replacement of orthopedic surgery, regeneration of periodontal ligaments, and to accelerate the wound healing process in diabetic ulcers (2-4). However, the…

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Rapid Healing and Reduced Erythema after Ablative Fractional Carbon Dioxide Laser Resurfacing Combined with the Application of Autologous Platelet-rich Plasma

Jung-Im Na, MD, Jee-Woong Choi, MD, Hye-Ryung Choi, PHD, Jeong-Bok Jeong, MSC, Kyoung-Chan Park, MD, PHD, Sang-Woong Youn, MD, PHD, and Chang-Hun Huh, MD, PHD


The introduction of fractional thermolysis revolutionized laser surgery, and this concept is now widely applied to various laser devices. Using a nonablative erbium-doped 1,550-nm laser, the creation of microcolumns of coagulation has been reported, leaving untreated skin between the treated columns. Because epidermal integrity is preserved, and…

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Face and Neck Revitalization With Platelet-rich Plasma (PRP): Clinical Outcome in a Series of 23 Consecutively Treated Patients

Alessio Redaelli MD, Domenico Romano MD, Antonio Marciano MD


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Platelet-rich fibrin matrix for improvement of deep nasolabial folds

Anthony P Sclafani, MD, FACS


Over 4.5 million nonsurgical procedures were performed in the US in 2008 for skin rejuvenation. Volume deficiency in areas of deeper folds, such as the nasolabial folds (NLFs), typically is treated with injectable dermal fillers. Disadvantages include the transient effects of…

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The Risk of Alar Necrosis Associated with Dermal Filler Injection



Soft tissue augmentation with temporary dermal fillers is a fast-expanding field and has become an integral part of many aesthetic physicians’ practices. According to the American Academy of Aesthetic Plastic Surgeons, 1,448,716 people received hyaluronic acid (HA) injections from plastic surgeons in 2007.

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Avoiding dermal filler complications

Richard N. Sherman, MD


Soft-tissue volume loss, particularly in the orbital and malar areas, is one of the hallmarks of the aging face. Age related volume loss, increased skin laxity, fat loss and redistribution, and diminished support from underlying muscle and bone result in the observable and sometimes profound changes seen in the aging face. These changes may manifest clinically…

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A New Classification of Lip Zones to Customize Injectable Lip Augmentation

Andrew A. Jacono, MD


The lips are an essential component of facial symmetry and aesthetics. Anthropometric studies have shown that wider and fuller lips in relation to facial width as well as greater vermilion height are a mark of female attractiveness.

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Analysis of Facial Skin Thickness: Defining the Relative Thickness Index

Richard Y. Ha, M.D., Kimihiro Nojima, M.D., William P. Adams, Jr., M.D., and Spencer A. Brown, Ph.D.


The determination of human skin thickness has been achieved through various methods, both in vivo and in vitro. Ultrasound and histometric analyses have been the most commonly used. However, absolute values of epidermal and dermal thicknesses have demonstrated variability among the different modalities, leaving questions regarding the ability to standardize or compare results of different studies.